Name: UGT1A9
SKU: 67115635
Price: 194.79 EUR
Availability: InStock
ISBN: 9786131329548

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Type

Physical Book

Publisher

Betascript Publishing

Language

English

Format

Paperback

Dimensions

22 x 0 cm

ISBN13

9786131329548

UGT1A9

New Book Imported to Austria

Delivery: 05 Oct - 07 Oct

194,79 €

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194,79 €

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Synopsis "UGT1A9"

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. UDP-glucuronosyltransferase 1-9 is an enzyme that in humans is encoded by the UGT1A9 gene. This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5 exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols.

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