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portada Synthesis and characterization of a pyrazole derivative-β-CD complex
Type
Physical Book
Language
English
Pages
56
Format
Paperback
Dimensions
22.9x15.2x0.3 cm
Weight
0.10 kg.
ISBN13
9786202801478

Synthesis and characterization of a pyrazole derivative-β-CD complex

Houcine Labiadh (Author) · Sonia Louiz (Author) · Raoudha Abderrahim (Author) · LAP Lambert Academic Publishing · Paperback

Synthesis and characterization of a pyrazole derivative-β-CD complex - Louiz, Sonia ; Labiadh, Houcine ; Abderrahim, Raoudha

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Synopsis "Synthesis and characterization of a pyrazole derivative-β-CD complex"

Amino pyrazole belongs to anti-inflammatory class, and is characterized by a low solubility in water. (In order to increase its solubility in water, inclusion complex of amino pyrazole with β-CD was obtained.)The inclusion complex obtained between AMP and β-cyclodextrin, was characterized by FT-IR, 1H NMR, 1H-1H NOESY, 13C NMR, DEPT, XHCOR, spectra, through TG analysis, DTA, DSC and Scanning Electron Microscopy (SEM). The stoichiometry of inclusion complex is 1:1 (guest-host) and K stability is 1.1 ×104 M-1.

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