Name: Molecular Targets in Protein Misfolding and Neurodegenerative Disease
Price: 107.92 EUR
Availability: InStock
Author: Pierfausto Seneci
ISBN: 9780128001868

portada Molecular Targets in Protein Misfolding and Neurodegenerative Disease

Molecular Targets in Protein Misfolding and Neurodegenerative Disease

Type

Physical Book

Publisher

Academic Press

Author

Pierfausto Seneci

Year

2014

Language

English

Pages

314

Format

Hardcover

ISBN13

9780128001868

Edition No.

Synopsis "Molecular Targets in Protein Misfolding and Neurodegenerative Disease "

Aimed at "drug discoverers" – i.e. any scientist who is interested in neurodegenerative diseases in general, and in finding disease-modifying treatments in particular – the first edition of Molecular Targets in Protein Misfolding and Neurodegenerative Disease will contain both a detailed, discipline-specific coverage (paragraphs on medicinal chemistry, on clinical and preclinical characterization of compounds in development, on target identification and validation, on genetic factors influencing a pathology, etc.) and a drug discovery-oriented, overall evaluation of each target (validation, druggability, existing leads, etc.). Together these will satisfy the needs of various audiences, including in vitro biologists, pharmacologists, medicinal chemists, etc. Written to provide a comprehensive coverage of disease-modifying mechanisms and compounds against neurodegenerative diseasesProvides a “drug discovery application oriented perspective, evaluating targets and candidates for their overall therapeutic potentialProvides discipline-specific chapters (medicinal chemistry, target validation, preclinical and clinical developmentProvides an overview on a number of molecular mechanisms (e.g. phosphorylation, chaperon refolding, ubiquitination, autophagy, microtubule transportation, protease cleavage, etc.) with relevance for any disease areaContains a more thorough description of the therapeutic relevance of ~10 specific molecular targets

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Molecular Targets in Protein Misfolding and Neurodegenerative Disease - Pierfausto Seneci

Synopsis "Molecular Targets in Protein Misfolding and Neurodegenerative Disease "

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