Name: Matrix Metalloproteinase
SKU: 56772848
Price: 80.11 EUR
Availability: InStock
Author: Ågren, Magnus S. ; Auf Dem Keller, Ulrich

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Type

Physical Book

Publisher

Mdpi AG

Author

Ågren, Magnus S. ; Auf Dem Keller, Ulrich

Language

English

Pages

262

Format

Hardcover

Dimensions

24.4x17x2.2 cm

Weight

0.77 kg.

ISBN13

9783039366484

Synopsis "Matrix Metalloproteinase"

Zinc-dependent matrix metalloproteinases (MMPs) belong to metzincins that comprise not only 23 human MMPs but also other metalloproteinases, such as 21 human ADAMs (a disintegrin and metalloproteinase domain) and 19 secreted ADAMTSs (a disintegrin and metalloproteinase thrombospondin domain). The many setbacks from the clinical trials of broad-spectrum MMP inhibitors for cancer indications in the late 1990s emphasized the extreme complexity of the participation of these proteolytic enzymes in biology. This editorial mini-review summarizes the Special Issue, which includes four review articles and 10 original articles that highlight the versatile roles of MMPs, ADAMs, and ADAMTSs, in normal physiology as well as in neoplastic and destructive processes in tissue. In addition, we briefly discuss the unambiguous involvement of MMPs in wound healing.

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Matrix Metalloproteinase - Ågren, Magnus S. ; Auf Dem Keller, Ulrich

Synopsis "Matrix Metalloproteinase"

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