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portada Lupus: Molecular and Cellular Pathogenesis
Type
Physical Book
Publisher
Author
Language
English
Pages
709
Format
Paperback
Dimensions
25.1x17.3x4.3 cm
Weight
1.27 kg.
ISBN13
9781475756869
Categories

Lupus: Molecular and Cellular Pathogenesis

Kammer, Gary M. (Author) · Humana · Paperback

Lupus: Molecular and Cellular Pathogenesis - Kammer, Gary M.

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Synopsis "Lupus: Molecular and Cellular Pathogenesis"

Leading basic and clinical investigators from around the world summarize the most recent research on the molecular and cellular origins of lupus. Their cutting-edge articles review the mechanisms underlying abnormal immunity and introduce the powerful new concept that a disorder of multiple genes underlies the abnormal immune response, leading directly to the development of lupus. This pathophysiology is shown to involve a wide variety of cell types, including T cells, B cells, natural killer cells, macrophages/monocytes, and endothelial cells. Over time, the resulting long-term inflammation causes irreversible cell destruction and, ultimately, organ failure. Lupus: Molecular and Cellular Pathogenesis is a masterful new synthesis of all the new knowledge emerging today about lupus. Its new perspectives will sharpen the focus of research and ultimately lead to better and more effective treatment.

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