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portada Genetics of the Mouse
Type
Physical Book
Publisher
Author
Language
English
Pages
408
Format
Paperback
ISBN13
9783662510162
Edition No.
1

Genetics of the Mouse

Jean Louis Guénet; Fernando Benavides; Jean-Jacques Panthier; Xavier Montagutelli (Author) · Springer · Paperback

Genetics of the Mouse - Jean Louis Guénet; Fernando Benavides; Jean-Jacques Panthier; Xavier Montagutelli

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Synopsis "Genetics of the Mouse"

This book, written by experienced geneticists, covers topics ranging from the natural history of the mouse species, its handling and reproduction in the laboratory, and its classical genetics and cytogenetics, to modern issues including the analysis of the transcriptome, the parental imprinting and X-chromosome inactivation. The strategies for creating all sorts of mutations, either by genetic engineering or by using mutagens, are also reviewed and discussed in detail. Finally, a last chapter outlines the methodology used for the analysis of complex or quantitative traits. The authors also discuss the importance of accurate phenotyping, which is now performed in the mouse clinics established worldwide and identify the limits of the mouse model, which under certain circumstances can fail to present the phenotype expected from the cognate condition in the human model. For each chapter an up-to-date list of pertinent references is provided. In short, this book offers an essential resource for all scientists who use or plan to use mice in their research.

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