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portada complications of cancer chemotherapy: proceedings of the plenary sessions of e.o.r.t.c., paris, june 1973
Type
Physical Book
Illustrated by
Publisher
Author
Year
2012
Language
English
Pages
142
Format
Paperback
Dimensions
24.4 x 17.0 x 0.8 cm
Weight
0.25 kg.
ISBN
3642808506
ISBN13
9783642808500
Categories

complications of cancer chemotherapy: proceedings of the plenary sessions of e.o.r.t.c., paris, june 1973

G. Mathe (Illustrated by) · R. K. Oldham (Illustrated by) · Springer · Paperback

complications of cancer chemotherapy: proceedings of the plenary sessions of e.o.r.t.c., paris, june 1973 - Mathe, G. ; Oldham, R. K.

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Synopsis "complications of cancer chemotherapy: proceedings of the plenary sessions of e.o.r.t.c., paris, june 1973"

G. MATHE and R. K. OLDHAM' Institut de Cancerologie et d'Immunogem!tique, Hopital Paul Brousse, Villejuif Since the last war, cancer chemotherapy has been the object of very intensive and expensive research. Nevertheless, its development has been very slow, and its ultimate potential is today somewhat in doubt. In doubt because it does not cure any cancer patients except a) females carrying placental choriocarcinoma, a semi-allogenic tumor, in which case, cure may be in- fluenced by immune rejection, and b) children suffering from Burkitt's tumor, where the probable reason for the cure is that all the neoplastic cells are in the cycle, which is a unique condition among all the human tumor varieties. Whether the long term survivors in acute leukemia, lymphomas, certain sarcomas and certain testicular tumors are "cures" will require longer follow-up. The idea that chemotherapy does not cure most cancer patients because all their neoplastic cells are not in cycle has led to the use of drug combinations. Whatever they are, "cocktail combinations" which are made up of drugs given according to any timing, or scientific combinations, based on pharmacodynamics, pharmaco- kinetics or cell kinetics data, are more toxic than single drugs, and are all the more toxic as the number of drugs in the combination is increased.

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