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portada Carboxylic Ionophores: Towards a New Approach to Drug Design
Type
Physical Book
Publisher
Author
Language
English
Pages
96
Format
Paperback
Dimensions
22.9x15.2x0.6 cm
ISBN13
9786209580420

Carboxylic Ionophores: Towards a New Approach to Drug Design

Khardli, Fatima Zahra (Author) · Our Knowledge Publishing · Paperback

Carboxylic Ionophores: Towards a New Approach to Drug Design - Khardli, Fatima Zahra

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Synopsis "Carboxylic Ionophores: Towards a New Approach to Drug Design"

Faced with the depletion of the therapeutic arsenal available to us, the search for new families of ligands in complexed form with different metals has become a new approach in the design of new therapeutic agents. This work explores an innovative path: the reworking of carboxylic polyether ionophores through metal complexation and/or structural modification. Through the synthesis and detailed characterization of new complexes and derivatives based on calcimycin, lasalocid, and monensin, this first volume lays the foundations for an alternative strategy based on the possible engineering of ionophores to make them therapeutic candidates adapted to contemporary challenges.

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