Ship to
Austria
0

My Account

  • argentina
  • chile
  • colombia
  • españa
  • méxico
  • perú
  • estados unidos
  • internacional

menu

Select your country

Americas

Europe

Rest of the world

portada affinity and efficacy
Type
Physical Book
Author
Publisher
Language
English
Pages
400
Format
Hardcover
Dimensions
23.6 x 16.0 x 2.0 cm
Weight
0.66 kg.
ISBN
9814322563
ISBN13
9789814322560
Categories

affinity and efficacy

Frederick J. Ehlert (Author) · World Scientific Publishing Company · Hardcover

affinity and efficacy - Ehlert, Frederick J.

Cheaper New Book Imported to Austria
Delivery: 24 Aug - 01 Sep Shipping: 16 to 20 business days.
349,93 €
Faster New Book Imported to Austria
Delivery: 06 Aug - 10 Aug Shipping: 4 to 5 business days.
357,16 €
Import costs and 10% VAT included in the price ✅
349,93 €

Choose the list to add your product or create one New List

Go to My Wishlists
Calculate shipping cost

Synopsis "affinity and efficacy"

The interaction of a drug with a receptor generates a code of information having components of affinity and efficacy. How this information is translated into a response depends on the unique cells, tissue, organ or system in which the receptor resides. This book describes how to analyze various responses to estimate the affinity and efficacy components of the initial drug-receptor interaction. More specifically, it describes how to measure the affinity and efficacy of drugs through the analysis of single receptor activity, the activation state of a population of receptors, and responses downstream from receptor activation. More light is thrown on ligand-gated ion channels and G protein-coupled receptors in this book.The topics discussed include radioligand binding, estimation of agonist affinity and efficacy, competitive antagonism, inverse agonism, allosteric agonists and modulators, agonist bias, modulation of pathway selectivity, and the estimation of ligand affinity for active and inactive receptor states. The natural history and structure of ligand-gated ion channels, G proteins, and G protein-coupled receptors are also discussed.

Customers reviews

More customer reviews
  • 0% (0)
  • 0% (0)
  • 0% (0)
  • 0% (0)
  • 0% (0)

Frequently Asked Questions about the Book

Is the book original?

All books in our catalog are Original.

In what language is the book written?

The book is written in English.

What is the format of this book?

The binding of this edition is Hardcover.

Questions and Answers about the Book

Do you have a question about the book? Login to be able to add your own question.

Opinions about Bookdelivery

More customer reviews