Name: Acute bilateral ophthalmoplegia related to paraneoplastic syndrome
SKU: 58632087
Price: 55.53 EUR
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Author: Kenmogne Kamdem, François ; Meli Tadida, Hota Isabelle
ISBN: 9786205897706

portada Acute bilateral ophthalmoplegia related to paraneoplastic syndrome

Acute bilateral ophthalmoplegia related to paraneoplastic syndrome

Type

Physical Book

Author

François Kenmogne Kamdem

Hota Isabelle Meli Tadida

Publisher

Our Knowledge Publishing

Language

English

Pages

Format

Paperback

Dimensions

22.9x15.2x0.3 cm

Weight

0.09 kg.

ISBN13

9786205897706

Synopsis "Acute bilateral ophthalmoplegia related to paraneoplastic syndrome"

There are various etiologies of ophthalmoplegia. Among these, a paraneoplastic syndrome should not be overlooked. We report on a patient with no history of neoplasia who presented with binocular diplopia associated with a cerebellar syndrome. The evolution is marked two days later by the involvement of the oculomotor nerves. Neurophysiological, ophthalmological and biological investigations came back normal. The circumstances in which the ophthalmoplegia occurred guided the etiological diagnosis. Given the clinical and paraclinical results, the diagnostic hypotheses of DEVIC disease and Miller Fischer syndrome were discussed. The latter was retained in view of the demonstration of the "anti Leucine rich glioma inactivated 1" antibody in the cerebrospinal fluid. After failure of corticosteroid therapy, a protocol of immunoglobulin treatment was instituted with a clinical evaluation at three months which showed a good evolution. This case highlights the diagnostic complexity of the neurological paraneoplastic syndrome, a rare entity that remains poorly known today by health professionals due to its diverse clinical presentations.