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portada Selected Topics in Myasthenia Gravis
Type
Physical Book
Publisher
Author
Language
English
Pages
94
Format
Hardcover
Dimensions
24.4x17x0.6 cm
Weight
0.35 kg.
ISBN13
9781838808297
Categories

Selected Topics in Myasthenia Gravis

Al-Zwaini, Isam Jaber ; Al-Mayahi, Ali (Author) · Intechopen · Hardcover

Selected Topics in Myasthenia Gravis - Al-Zwaini, Isam Jaber ; Al-Mayahi, Ali

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Synopsis "Selected Topics in Myasthenia Gravis"

Myasthenia gravis is a rare potentially fatal chronic autoimmune disorder. Circulating autoantibodies directed against components of the neuromuscular junction of skeletal muscles, most commonly nicotinic acetylcholine receptor and associated protein in the postsynaptic membrane, block neuromuscular transmission resulting in muscle weakness. This muscle weakness typically worsens with continued activity, improves on rest, and is of variable severity ranging from mild ocular muscle weakness to severe generalized muscle weakness, involving the respiratory muscle with impending respiratory failure. The worldwide prevalence of myasthenia gravis is 100-200 per million population, affecting more than 700,000 people all over the world. The prevalence rate has increased since the 1950s due to improved diagnostic precision and decreased mortality rate.

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