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portada Homology Modeling of Human Nk-1 Receptor and Docking Study: Structure Based Drug Design
Type
Physical Book
Language
English
Pages
92
Format
Paperback
ISBN13
9783659804205

Homology Modeling of Human Nk-1 Receptor and Docking Study: Structure Based Drug Design

Manish K. Gupta; Viney Kumar (Author) · Lap Lambert Academic Publishing · Paperback

Homology Modeling of Human Nk-1 Receptor and Docking Study: Structure Based Drug Design - Manish K. Gupta; Viney Kumar

New Book Imported to Austria
Delivery: 14 Jul - 16 Jul Shipping: 12 to 13 business days.
60,26 €
Import costs and 10% VAT included in the price ✅
60,26 €

Synopsis "Homology Modeling of Human Nk-1 Receptor and Docking Study: Structure Based Drug Design"

Neurokinin-1 (NK-1) receptor regulates many biological functions related to cancer, such as tumor cell proliferation, angiogenesis and migration of tumor cells for invasion and metastasis. The NK-1 receptor antagonists specifically inhibit tumor cell proliferation, migration of the tumor cells and show antiangiogenic effect. Therefore, the development of NK-1 antagonists for the treatment of cancer is of current interest. The 3D structure of NK-1 is not available from protein data bank. This hampers the design of selective NK-1 antagonists. This book describes the homology modeling of the human NK-1 receptor using multiple templates to provide structural basis for the design of new NK-1 inhibitors and anticancer agents. The authors anticipate that the book will be very useful for the researchers who are working on the design and development of NK-1 receptor antagonists and anticancer agents.

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