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portada Glycobiology of the Nervous System
Type
Physical Book
Publisher
Language
English
Pages
501
Format
Hardcover
Dimensions
23.4 x 15.6 x 2.9 cm
Weight
0.89 kg.
ISBN13
9783031123894
Edition No.
0002

Glycobiology of the Nervous System

Cara-Lynne Schengrund (Illustrated by) · Robert K. Yu (Illustrated by) · Springer · Hardcover

Glycobiology of the Nervous System - Schengrund, Cara-Lynne ; Yu, Robert K.

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Synopsis "Glycobiology of the Nervous System "

Chapter TitlesIntroduction to the complexity of cell surface and tissue matrix glycoconjugates Cells of the central nervous system: An overview of their structure and functionSynthesis, processing, and function of N-glycans in N-glycoproteinsSynthesis of O-linked glycoconjugates in the nervous systemChemistry and function of glycosaminoglycans in the nervous systemStructural analysis of oligosaccharides and glycoconjugates using NMRGlycans and carbohydrate-binding/transforming proteins in axon physiologyNeurological consequences of congenital disorders of glycosylationBrain O-GlcNAcylation: from molecular mechanisms to clinical phenotypeGanglioside microdomains on cellular and intracellular and membranes regulate neuronal cell fate determinationGangliosides and cell surface ganglioside glycohydrolases in the nervous systemNeuronal ganglioside and GSL metabolism in health and disease Cascades of secondary metabolic errors can generate complex pathologies (in LSDs)Gangliosides in neurodegenerative diseasesFunctional impairment of the nervous system with glycolipid deficienciesCarbohydrates: binding sites and potential drug targets for neural-affecting pathogensAntibodies to glycolipids in Guillain-Barré syndrome, Miller Fisher syndrome and related autoimmune neurological diseases

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